Trial flights start later this year between Doncaster Sheffield Airport and Amsterdam.
Local company HiAir said it wants to test the route in a bid to attract business people and holidaymakers.
The first flight is scheduled for September 5 and is bookable now.
Mike Morton, Doncaster Sheffield Airport director said: "This is a great opportunity for the region to get behind a local company who are committed to offering travellers a high quality service to a key European airport.
"We know from past experience that Amsterdam is a destination that businesses in particular are keen to see served from this airport and we hope that interest from passengers will see this service come to fruition later in the year."
Flights will be on a Jetstream 32, with 19 seats.
HiAir will also be offering a concierge programme and executive travel options both to and from the airport for professionals with chauffeured cars and helicopter transfers.
