Flybe is to launch year-round flights from London City and Manchester to Amsterdam in October.
Tickets are on sale now at www.flybe.com with one way fares from £39.9 including taxes and charges.
The airline will operate daily flights between Manchester and Amsterdam using 88-seat Embraer 175 jet aircraft from October 26.
Weekend flights will operate from London City on Saturday morning and Sunday evenings on a 78-seat Bombardier Q400 aircraft from November 1.
Chief commercial officer Paul Simmons said: "Flybe is the largest scheduled airline by the volume of traffic movements at Manchester and, based on existing evidence, the demand for flights between there and Amsterdam is already extremely high.
"This is why we have conveniently scheduled our new flights to ensure the best possible times for our business customers and also for those making Flybe connections through our Manchester hub onward to Schiphol."
