Flybe franchise partner Blue Islands is to operate new services to Southend and Liverpool this summer.
A daily Southend service will start on May 20, while a twice-weekly Liverpool flight will start on May 21, operating on Tuesdays and Saturdays.
Introductory one-way prices start from £29.99.
Blue Islands chief executive Rob Veron said: "We know locally there is a shared aspiration for more air links from Guernsey, particularly alternatives to London.
"This extra connectivity means increased visibility for Guernsey in new UK markets where potential new visitors now have easy access to our island."
