Swiss International Air Lines will launch flights fom Dublin and Geneva this summer.
From June 26, it will operate four weekly flights on the route on A320 aircraft with around 150 seats.
"In opening our new route between Dublin and Geneva, we are responding to a clear demand on the part of both our leisure and our business customers," said director for UK and Ireland Felix Rodel.
SWISS already operates a year-round service from Dublin to Zurich with up to nine flights per week during the peak summer season.
The new Geneva service will fly on Mondays, Wednesdays, Fridays, and Sundays.
Tickets are on sale now from €45 one way.
