Thomas Cook Airlines will launch a weekly flight from Glasgow to Las Vegas in summer 2015.
Operating each Monday on the airlines Airbus A330 fleet, the new flights will begin on May 4 and run up until the October 31.
CEO Christoph Debus said: "It’s fantastic news that we are able to start a regular flight to Las Vegas next summer, as a result of the great support and feedback we’ve received when we’ve operated individual flights to the US."
Fares will start from £499 return.
The news comes as Thomas Cook announced plans to operate three long haul routes from London Stansted.
